Kavishini Apasamy

Abstract The hippocampus and cerebellum are traditionally considered to support distinct memory systems, yet evidence from nonhuman species indicates a close relationship during spatial-mnemonic behaviour, with hippocampal projections to and from several cerebellar regions. However, little is known about this relationship in humans. To address this, we applied seed-based functional connectivity analysis to resting-state fMRI data from 479 cognitively normal participants aged 18–88 years.

Abstract Although the hippocampus and cerebellum are traditionally considered to support distinct memory systems, evidence from nonhuman species indicates a close bidirectional relationship during learning and navigational behaviour, with the hippocampus projecting to - and receiving input from - several cerebellar regions. However, little is known about the nature and topography of hippocampal-cerebellar connectivity in the human brain.