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Kavit Amin

As seen in: BioRxiv, Future Medicine
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Articles

Antioxidant Poly(propylene sulfide) Nanoparticles Ameliorate Ischemia-Reperfusion Injury and Improve Porcine Kidney Function Post-Transplantation

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By John Stone, Richard d’Arcy, Abbey Geraghty, Kavit Amin
| dx.doi.org
Biological and Medical Applications of Materials and InterfacesOctober 15, 2025 John P.
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Antioxidant Polysulfide Nanoparticles Ameliorate Ischemia-Reperfusion Injury and Improve Porcine Kidney Function Post-Transplantation

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By John Stone, Richard D'Arcy, Abbey Geraghty, Kavit Amin
| BioRxiv
Abstract Ischemia-reperfusion injury (IRI) is a significant complication in kidney transplantation, often affecting the viability and function of organs. Normothermic machine perfusion (NMP) is a technique used to improve the condition of organs prior to transplantation. In this study, we show that incorporating antioxidant poly(propylene sulfide) nanoparticles (PPS-NPs) during cold-storage and NMP significantly enhances its efficacy in reducing IRI upon porcine kidney transplantation.
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Polysulfide Nanoparticles Ameliorate Ischaemia Reperfusion Injury in Renal Transplantation and Improve Kidney Function Post-Transplantation

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By John Stone, Richard D'Arcy, Abbey Geraghty, Kavit Amin
| BioRxiv
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