Kay Wye Sabrina on Muck Rack

Kay Wye Sabrina

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Cluster Analysis of Younger-Onset Type 2 Diabetes in an Asian Cohort Reveals Distinct Subgroups With Differential Pathophysiology and Outcomes

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By Kai Xiang, Chee Fang, Kay Wye Sabrina, Wan Ting Lovynn
| Diabetes Spectrum
Younger-onset type 2 diabetes (T2D, onset <40 years) represents a growing global health challenge, characterized by heterogenous pathophysiology and accelerated complications. Current ‘one-size-fits-all” treatment approaches may be inadequate for this population. To address this heterogeneity, we performed clinical variable-based clustering using BMI, onset age, HbA1c and HOMA2 indices in 717 participants across discovery and validation cohorts.
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