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Kaylen R. Meeks on Muck Rack

Kaylen R. Meeks

As seen in: Wiley Online Library, MDPI
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Articles

Targeting a Unique Cysteine Residue to Achieve Isoform-Selective Inhibition of the Proline Biosynthetic Enzyme Pyrroline-5-Carboxylate Reductase 2 Click to copy article link Article link copied!

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By Kaylen R. Meeks, Tyrell C. Rossman, Gunjan Purohit
| dx.doi.org
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Crystallographic Fragment Screening of a Bifunctional Proline Catabolic Enzyme Reveals New Inhibitor Templates for Proline Dehydrogenase and L-Glutamate-γ-semialdehyde Dehydrogenase

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By Kaylen R. Meeks, Alexandra N. Bogner, Jay C. Nix, John Tanner
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Screening a knowledge‐based library of low molecular weight compounds against the proline biosynthetic enzyme 1‐pyrroline‐5‐carboxylate 1 (PYCR1)

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By Kaylen R. Meeks, Alexandra N. Bogner, John Tanner
| Wiley Online Library Verified
Supporting Information Filename Description pro5072-sup-0001-supinfo.xlsxExcel 2007 spreadsheet , 13.4 KB Data S1. Supporting information. REFERENCES , , , , , , et al. Towards automated crystallographic structure refinement with phenix.refine. Acta Crystallogr D Biol Crystallogr. 2012; 68(Pt 4): 352–367. , , , , , , et al. Increased mitochondrial proline metabolism sustains proliferation and survival of colorectal cancer cells. PLoS One. 2022; 17(2):e0262364. , , .
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