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Ke-Ying Zhu on Muck Rack

Ke-Ying Zhu

As seen in: Frontiers in Immunology
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Articles

Macrophage polarization in Sjögren’s syndrome: from mechanisms to therapeutic translation

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By Huan Li, Song-Wei Li, Ke-Ying Zhu, Xi-Meng Li, Qian-Lei Xu, Cheng-Zhi Wang, Shang-Wen Wu, Zhi-Na Zhao, Hui-Jun Guo
| Frontiers in Immunology
Abstract Sjögren’s syndrome (SS) is a chronic systemic autoimmune disease characterized by damage to exocrine glands, and no effective treatment is currently available to reverse glandular fibrosis. As core effector cells of innate immunity, macrophages play a pivotal role in the dynamic imbalance of polarization states, which critically influences inflammation initiation, tissue injury, and irreversible fibrosis in SS.
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