Loading metrics Open Access Peer-reviewed Research Article Citation: Jahn S, Fraser K, Gaythorpe KAM, Wainwright CM, Ferguson NM (2025) Evaluating the role of observational uncertainty in climate impact assessments: Temperature-driven yellow fever risk in South America. PLOS Clim 4(6): e0000601. https://doi.org/10.1371/journal.pclm.0000601 Editor: Shanshan Li, Monash University, AUSTRALIA Received: March 17, 2025; Accepted: June 2, 2025; Published: June 25, 2025 Copyright: © 2025 Jahn et al.