Kelly Hughes

Loading metrics Open Access Peer-reviewed Research Article Citation: Hughes K, Nguyen D, Aberoumand M, Ford H, Clarke E, Banos Lopez N, et al. (2026) Prognostic value of cervical length for spontaneous preterm birth in asymptomatic women with singleton pregnancy: An individual participant data meta-analysis. PLoS Med 23(6): e1004653.

1 Introduction Gene expression profiling (GEP) has emerged as a groundbreaking tool in cancer diagnosis. This technology allows researchers and clinicians to stratify tumour subtypes and evaluate the expression of prognostically significant molecular targets. For example, one of the first successful applications of GEP in humans was the PAM50 gene panel, which utilised limited gene panels to subtype breast cancers and provided prognostic information to clinicians [1].

Abstract Introduction: The pentaazamacrocyclic superoxide dismutase mimetic, Avasopasem Manganese (AVA), has been shown in clinical trials to reduce the severity and duration of acute oral mucositis (OM) and acute esophagitis in patients treated for head and neck and lung cancers, respectively, by radiotherapy using conventional fractionation protocols.