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Kendra Kumar Shrestha on Muck Rack

Kendra Kumar Shrestha

As seen in: BioRxiv
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Articles

Optical Control of Cell-Surface and Endomembrane-Exclusive β-Adrenergic Receptor Signaling

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By Waruna Thotamune, Sithurandi Ubeysinghe, Mahmoud Mostafa, Kendra Kumar Shrestha
| BioRxiv
Abstract Beta-adrenergic receptors (βARs) are G protein-coupled receptors (GPCRs) that mediate catecholamine-induced stress responses, such as heart rate increase and bronchodilation. In addition to signals from the cell surface, βARs also broadcast non-canonical signaling activities from the cell interior membranes (endomembranes). Dysregulation of these receptor pathways underlies severe pathological conditions.
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