Kenneth D Belanger

Abstract Mass deworming programs using anthelmintic drugs are a common public health strategy for controlling soil-transmitted helminth (STH) infections in high-risk, low-income countries. However, whether routine deworming induces long-term changes in gut microbiome composition remains unclear. We used longitudinal data to examine how anthelmintics alter the gut microbiome profiles of Ethiopian children.

Loading metrics Open Access Peer-reviewed Research Article Citation: Taye B, Mekonnen Z, Belanger KD, Davenport ER (2024) Gut-microbiome profiles among Soil-transmitted helminths (STHs) infected Ethiopian children enrolled in the school-based mass deworming program. PLoS Negl Trop Dis 18(10): e0012485.

Abstract Subconcussive head impacts (SHIs) are a public health concern amongst at-risk populations. SHIs are hits to the head that do not typically generate symptoms and are unlikely to meet diagnostic criteria for mild traumatic brain injury (mTBI). Changes in the gut microbiome have been associated with mTBIs and implicated in both acute recovery from and neurodegenerative pathologies associated with repeated mTBI.