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Kerstin Miebach on Muck Rack

Kerstin Miebach

As seen in: Cell Metabolism
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Articles

Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain

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By Chaitali Mukherjee, Tina Kling, Belisa Russo, Kerstin Miebach
| Cell Metabolism Verified
Highlights • A screen in Drosophila identifies glial molecules with vital functions for neurons • Depletion of glial ferritin heavy chain results in iron-mediated axonal damage • Ferritin heavy chain is secreted by oligodendrocytes in mice • Disrupting its release or expression results in neuronal damage in aged mice Summary An evolutionarily conserved function of glia is to provide metabolic and structural support for neurons.
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