Kieran G. Meade on Muck Rack

Kieran G. Meade

Leinster, Mullingar
As seen in: PLOS ONE, BioRxiv
Prof & Dir of MSc in Animal Sc in UCD Dublin. Interests in teaching, supporting immunity & 1health. Opinions own. PS that's Dolly in pic!
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Articles

Impact of β-defensin 103 (DEFB103) copy number variation on bull sperm parameters and post-insemination uterine gene expression

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By Ozge Sidekli, Edward J. Hollox, Sean Fair, Kieran G. Meade
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Sidekli O, Hollox EJ, Fair S, Meade KG (2025) Impact of β-defensin 103 (DEFB103) copy number variation on bull sperm parameters and post-insemination uterine gene expression. PLoS ONE 20(2): e0319281. https://doi.org/10.1371/journal.pone.0319281 Editor: Ayman A.
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The role of β-defensin 103 (DEFB103) copy number variation in bull fertility

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By Ozge Sidekli, Sean Fair, Kieran G. Meade, Ed J Hollox
| BioRxiv
Abstract Pregnancy rates for elite bulls used in artificial insemination (AI) can vary significantly and therefore the identification of molecular markers for fertility and targets to improve bull selection is important. β-defensins are peptides which have diverse regulatory roles in sperm function across multiple species.
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β-defensin gene copy number variation in cattle

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By John Oketch, Kieran G. Meade, Ozge Sidekli, Sean Fair
| BioRxiv
Abstract β-defensins are peptides with antimicrobial roles, characterized by a conserved tertiary structure. Beyond antimicrobial functions, they exhibit diverse roles in both the immune response and fertility, including involvement in sperm maturation and function. Copy number variation (CNV) of β-defensin genes is extensive across mammals, including cattle, with possible implications for reproductive traits and disease resistance.
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