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Articles

MAXTIA: A high-throughput platform for rapid functional epitope mapping by kinetic screening of mutant libraries

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By Kihoon Kim, Ryo Matsunaga, Takanori Yokoo
| Wiley Online Library Verified
1 INTRODUCTION An epitope, also known as an antigenic determinant, is a specific region of an antigen that is recognized and bound by the antigen binding site of an antibody. Epitope mapping is the experimental process of identifying and characterizing specific binding sites at the molecular or amino acid residue level (Sharon et al., 2014; Talucci et al., 2024), linking molecular recognition to function (Sela-Culang et al., 2013).
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Biomechanical evaluation of structural integrity after tibial plateau leveling osteotomy in dogs using finite element analysis

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By Kihoon Kim, Heung-Myong Woo, Junhyung Kim, Hyun-Seok Joh
| Nature Verified
Abstract Cranial cruciate ligament rupture is one of the most common orthopedic problems in dogs, and tibial plateau leveling osteotomy (TPLO) is the preferred surgical treatment. This study aimed to evaluate biomechanical interactions between bone and implant under various loading conditions (standing, walking, trotting, and galloping) after TPLO using finite element analysis, and to assess the risk of fatigue failure.
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Case Report: Surgical management of mandibular oral histiocytic sarcoma in a ragdoll cat with favorable outcome

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By Byung-Joon Seung, Byungho Lee, Jungwhan Chon, Kihoon Kim, Jongmun Cho
| Frontiers
Abstract Feline oral histiocytic sarcoma (HS) is an exceptionally rare malignancy with limited clinical characterization and a poor prognosis. This report describes a case of mandibular HS in a 6-year-old Ragdoll cat that achieved a favorable local control following surgical management alone. The cat presented with left mandibular swelling, and diagnostic imaging revealed a poorly demarcated mass with extensive osteolysis of the mandible.
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