Kim Klein

1 INTRODUCTION Infections caused by gram-positive bacteria pose a significant threat to critically ill children.1, 2 Teicoplanin (Targocid®), a glycopeptide antibiotic, is widely used to treat such infections, including those caused by Staphylococcus aureus and streptococcal species.2 Although not registered for prophylactic use, it is frequently used off-label for surgical or oncology-related prophylaxis.3, 4 Because of its favourable spectrum of activity, efficacy and minimal reported...