This paper is only available as a PDF. To read, Please Download here. Abstract: Core outcome sets (COS) are critically important outcomes that should be measured in clinical trials. Their absence in atopic dermatitis (AD) is a form of research waste and impedes combining evidence to inform patient care. Here, we articulate the rationale for COS in AD and review the work of the international Harmonising Outcome Measures for Eczema (HOME) group from its inception in Munich, 2010.