Kimberley Bryon-Dodd

Immunotherapy has revolutionized cancer treatment, yet the drug discovery process to develop new biotherapeutic antibodies remains arduous. However, significant advances in antibody technology such as phage display have enabled fully human antibodies to be developed from animal-free libraries for just about any antigen. The specificity of monoclonal antibodies (mAb) enables them to precisely target cancer cells by binding to cell surface markers.

Anti-Müllerian hormone may play role in infertility associated with PCOS 14 March 2022 Appeared in BioNews 1136 A new preclinical study using human tissue grafted into mice has indicated that high levels of anti-Müllerian hormone (AMH) may contribute to fertility problems and other symptoms associated with polycystic ovary syndrome (PCOS).

Genetic variants discovered that increase risk of PCOS 22 November 2021 Appeared in BioNews 1122 A genome-wide association study has identified three genetic variants associated with increased risk of polycystic ovary syndrome (PCOS) in Finnish and Estonian women. Two of these variants identified affect the CHEK2 gene.