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Kirthika Kumar on Muck Rack

Kirthika Kumar

As seen in: AIChE Journal, Nature, BioRxiv
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Articles

AI‐assisted warfarin dose optimisation with CURATE.AI for clinical impact: Retrospective data analysis

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By Kirthika Kumar, Shi-Bei Tan, Sarah Tang, Mathias Egermark
| AIChE Journal Verified
Physician-guided warfarin dosing lead to frequent deviations from INR and adverse events. CURATE.AI, an artificial intelligence-derived platform, has potential as a Clinician Decision Support System to improve accuracy of warfarin dosing decisions compared to physician-guided dosing. This can facilitate the effective use of affordable warfarin with a well-established safety profile, without the need for costly, new oral anticoagulants.
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Personalized dose selection for the first Waldenström macroglobulinemia patient on the PRECISE CURATE.AI trial - npj Digital Medicine

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By Agata Blasiak, Li Chong, Xavier Tadeo, Kirthika Kumar, Raghav Sundar, Yoann Sapanel
| Nature Verified
Abstract The digital revolution in healthcare, amplified by the COVID-19 pandemic and artificial intelligence (AI) advances, has led to a surge in the development of digital technologies. However, integrating digital health solutions, especially AI-based ones, in rare diseases like Waldenström macroglobulinemia (WM) remains challenging due to limited data, among other factors.
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Influence of amino acid substitutions in capsid proteins of coxsackievirus B5 on free chlorine and thermal inactivation

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By Shotaro Torii, Jérôme Gouttenoire, Aleksandar Antanasijevic, Kirthika Kumar
| BioRxiv
Abstract The sensitivity of enteroviruses to disinfectants varies among genetically similar variants and coincides with amino acid changes in capsid proteins, though the effect of individual substitutions remains unknown. Here, we employed reverse genetics to investigate how amino acid substitutions in coxsackievirus B5 (CVB5) capsid proteins affect its sensitivity to free chlorine and heat treatment.
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