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Kjetil Bårdsen on Muck Rack

Kjetil Bårdsen

As seen in: Wiley Online Library
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Articles

Fatigue in Parkinson's Disease: A Proteomic Study of Cerebrospinal Fluid

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By Even Birkeland, Proteomics Unit, Marie Austdal, Kjetil Bårdsen
| Wiley Online Library Verified
Many factors have been linked to fatigue in patients with Parkinson's disease (PD), including age, female sex, disease severity, depression, cognition, sleep disturbances, activities of daily living, and the use of dopamine agonists.1, 2 While these sociodemographic and non-motor phenomena undoubtedly impact fatigue, they do not elucidate the molecular mechanisms underlying it.
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Fatigue and expression of heat shock genes in plaque type psoriasis

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By Kjetil Bårdsen, Inger M. Skoie, Mari M. Nilsen, Tore Grimstad
| Wiley Online Library Verified
Background Chronic fatigue is common in psoriasis, and heat shock proteins (HSP) have been postulated to influence fatigue. Objective To evaluate gene expression patterns of selected HSPs in psoriasis patients with high versus low fatigue. Methods Fatigue was assessed using the fatigue Visual Analoge Scale and disease activity by the Psoriasis Area and Severity Index.
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Considerably Lower Levels of Hypocretin-1 in Cerebrospinal Fluid Is Revealed by a Novel Mass Spectrometry Method Compared with Standard Radioimmunoassay

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By Markku Partinen, Kjetil Bårdsen, Michaela D. Gjerstad, Ingeborg Kvivik
| American Chemical Society
Low levels of hypocretin-1 (Hcrt1) in cerebrospinal fluid (CSF) are associated with narcolepsy type 1 (NT1). Although immunoassays are prone to antibody batch differences, detection methods and variation between laboratories, the standard method for Hcrt1 measurement is a radioimmunoassay (RIA). Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) is an antibody- and radioactive free alternative for precise measurement of Hcrt1.
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