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Kommidi Harikrishna on Muck Rack

Kommidi Harikrishna

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Articles

A fluorescent, [18F]-positron-emitting agent for imaging PMSA allows genetic reporting in adoptively-transferred, genetically-modified cells

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By Hua Guo, Kommidi Harikrishna, Yogindra Vedvyas, Jaclyn E McCloskey
| American Chemical Society
Abstract Clinical trials that involve genome-edited-cells are growing in popularity, where CAR-T immunotherapy and CRISPR editing are more recognized strategies. Genetic reporters are needed to localize the molecular events that these cells cause in patients. Specifically, a non-immunogenic genetic reporter is urgently needed as current reporters are immunogenic due to derivation from non-human sources.
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