Konstantina Foti on Muck Rack

Konstantina Foti

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Articles

Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome

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By Monica Chandra, Johan P Zeelen, Monique van Straaten, Konstantina Foti
| PLOS
Crystal structure of VSG531 shows close homology to class A2 members We also crystallized mVSG531, predicted to be of the Class A2 group, determining its structure to 1.95Å resolution (Figs 3 and S1B and S1 Table and Methods). Consistent with bioinformatic analyses, mVSG531 is very similar to the structures of other Class A2 members solved from BSF VSGs, particularly VSG1 and VSG2, aligning to each with a RMSD of 2.1Å over 354 residues and 2.4Å over 347 residues, respectively (Fig 3A, [48,49]).
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