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Koralege C. Pathmasiri on Muck Rack

Koralege C. Pathmasiri

As seen in: Nature, BioRxiv
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Articles

Gel-assisted mass spectrometry imaging enables sub-micrometer spatial lipidomics - Nature Communications

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By Yat Ho Chan, Koralege C. Pathmasiri, Dominick Pierre-Jacques, Stephanie M. Cologna, Maddison C. Hibbard
| Nature Verified
Abstract A technique capable of label-free detection, mass spectrometry imaging (MSI) is a powerful tool for spatial investigation of native biomolecules in intact specimens. However, MSI has often been precluded from single-cell applications due to the spatial resolution limit set forth by the physical and instrumental constraints of the method.
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Gel-assisted mass spectrometry imaging

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By Yat Ho Chan, Koralege C. Pathmasiri, Stephanie M. Cologna, Dominick Pierre-Jacques
| BioRxiv
New Results doi: https://doi.org/10.1101/2023.06.02.543480 Abstract Compatible with label-free detection and quantification, mass spectrometry imaging (MSI) is a powerful tool for spatial investigation of biomolecules in intact specimens. Yet, the spatial resolution of MSI is limited by the method's physical and instrumental constraints, which often preclude it from single-cell and subcellular applications.
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Mass spectrometry imaging reveals ganglioside and ceramide localization patterns during cerebellar degeneration in the Npc1−/− mouse model

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By Fernando Tobias, Stephanie M. Cologna, Koralege C. Pathmasiri
| link.springer.com
Analytical and Bioanalytical Chemistry September 2019, Volume 411, Issue 22, pp 5659–5668 | Cite as Paper in Forefront First Online: 29 June 2019 Shares 218 Downloads Abstract Mass spectrometry imaging (MSI) is a powerful tool to perform untargeted mapping of biomolecules in situ.
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