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Kosumo Numao on Muck Rack

Kosumo Numao

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Articles

MiR-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy

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By Masashi Fukuoka, Hiromi Fujita, Kosumo Numao, Yasuko Nakamura
| Nature Verified
Abstract Parabiosis experiments suggest that molecular factors related to rejuvenation and aging circulate in the blood. Here, we show that miR-199-3p, which circulates in the blood as a cell-free miRNA, is significantly decreased in the blood of aged mice compared to young mice; and miR-199-3p has the ability to enhance myogenic differentiation and muscle regeneration.
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