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Koushick Sivakumar on Muck Rack

Koushick Sivakumar

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Articles

A metal ion mediated functional dichotomy encodes plasticity during translation quality control - Nature Communications

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By Katta Suma, Shobha P Kruparani, Jotin Gogoi, Koushick Sivakumar
| Nature Verified
Abstract Proofreading during translation of the genetic code is a key process for not only translation quality control but also for its modulation under stress conditions to provide fitness advantage. A major class of proofreading modules represented by editing domains of alanyl-tRNA synthetase (AlaRS-Ed) and threonyl-tRNA synthetase (ThrRS-Ed) features a common fold and an invariant Zn2+ binding motif across life forms.
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