Koushik Muralidharan

The authors have declared no competing interest. This study did not receive any funding I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: All samples were collected with informed consent under Partners institutional review board (IRB)-approved protocol 2017P001581.