During pregnancy, the placenta is an important transient organ that connects the mother and the fetus, which continuously delivers oxygen, nutrients, and metabolites to the fetus to maintain the normal growth and development of the fetus.1,2 Placental development is a complex process that involves a transformation of the single-layer embryonic trophectoderm (TE) at the blastocyst stage into a dense, multinucleated, multicellular, and multi-layered organ.3,4 Due to the rapid growth of the...