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Kuangying Yang

As seen in: Nature, MDPI
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Articles

Integrated genomic analysis of NF1-associated peripheral nerve sheath tumors: an updated biorepository dataset - Scientific Data

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By Stavriani C Makri, Kuangying Yang, Calixto-Hope G. Lucas, Jiawan Wang, Robert J. Allaway
| Nature Verified
Abstract Neurofibromatosis type 1 (NF1) is an inherited neurocutaneous condition that predisposes to the development of peripheral nerve sheath tumors (PNST) including cutaneous neurofibromas (CNF), plexiform neurofibromas (PNF), atypical neurofibromatous neoplasms of uncertain biologic potential (ANNUBP), and malignant peripheral nerve sheath tumors (MPNST).
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A Sequencing Overview of Malignant Peripheral Nerve Sheath Tumors: Findings and Implications for Treatment

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By Kangwen Xiao, Kuangying Yang, Angela C. Hirbe
| MDPI
1. Overview of MPNSTs The earliest MPNST in a human can be traced back to 1952, which was described as an unclassified tumor which resembles a neurofibroma in a Caucasian male [1]. In 1984, Ducatman et al. reported 16 cases of MPNSTs in children under 16, with a mean survival of only 1.8 years [2]. In 1986, a study reviewed 120 cases of MPNSTs and concluded that total resection of the tumor could improve the prognosis of the MPNST.
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