Kuk Hui Son

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WHAT IS THE CURRENT KNOWLEDGE ON THE TOPIC? Various factors could affect drug pharmacokinetics in patients undergoing surgery with cardiopulmonary bypass (CPB). However, the pharmacokinetics of sufentanil in these patients remain improperly characterized. WHAT QUESTION DID THIS STUDY ADDRESS? This study aimed to develop a population pharmacokinetic model for sufentanil in adult patients undergoing CPB and identify the clinical factors affecting its pharmacokinetic profiles.

Open AccessArticle by Jihye Bang 1,†, Kuk Hui Son 2,†, Hye-Ryeon Heo 1, Eunsook Park 1, Hyun-Jeong Kwak 3, Kyung-Ok Uhm 1, Myung-Hee Chung 4, Young-Youl Kim 1 and Hyun Joung Lim 1,* 1 Division of Allergy and Respiratory Disease Research, Department of Chronic Disease Convergence Research, National Institute of Health, Osong Health Technology Administration Complex 187, Osongsaengmyeong 2-ro, Osong-eup, Heungdeok-gu, Cheongju-si 28159, Republic of Korea 2 Gachon University Gil Medical Center,...