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Articles by Kun Ma
Application Research of Agile Concepts in Teacher Development in the Big Data Era
In examining the trends characteristic of the digital era, it is essential to consider both the challenges and opportunities faced by educational institutions, as well as the critical role of big data in investigating the education sector. The abundance of data, ranging from official statistics to intricate social patterns, offers fresh insights for addressing the needs of educators and learners, facilitating educational innovation, and enhancing service quality.
Integrating CT Radiomics and Machine Learning for Preoperative Assessment of STAS Grading and Prognostic Stratification in Lung Adenocarcinoma
Abbreviations ACC (accuracy) AdaBoost (Adaptive Boosting) AUC (area under the curve) CEA (carcinoembryonic antigen) CTR (consolidation tumor ratio) DCA (Decision Curve Analysis) DT (Decision Tree) GBDT (Gradient Boosting Decision Tree) KNN (K-Nearest Neighbors) LASSO (Least Absolute Shrinkage and Selection Operator Regression) LightGBM (Light Gradient Boosting Machine) LR (Logistic Regression) LUAD (lung adenocarcinoma) MRMR (Minimum Redundancy Maximum Relevance) NB (Naive Bayes) NPV...
BCAT1 inhibits crotonate-related epigenetic modulation of metabolic genes in tumor-associated macrophages to counter immunosuppression
Abstract The heterogeneous and immunosuppressive tumor microenvironment (TME) in hepatocellular carcinoma (HCC) contributes to poor immunotherapy responses. Tumor-associated macrophages (TAM) are central to the immunosuppressive TME, but how metabolic programs regulate TAM pro-tumorigenic functions remain incompletely understood. Here, we identify branched-chain amino acid transaminase 1 (BCAT1) as a metabolic checkpoint in TAMs constraining tumor progression.
Consumer-Level Tai-Chi Teaching Assistance System: Feedback-Based Teaching of Traditional Chinese Sports in University Environments Integrating Visual Information and Virtual Reality
Abstract To overcome limited feedback and personalization in large university Tai Chi classes, we build a VR-based teaching system that pairs real-time visual interaction with Unity3D. Depth cameras track students’ skeletons, while Dynamic Time Warping and Hausdorff distance compare their trajectories to expert templates. A Kalman filter smooths data, and a decision-tree classifier instantly grades each move, delivering individualized cues and progress reports.
Coupling Tensile Strain and Electronic Modulation in Mesoporous PdMo Metallene Nanoveins for Improved Oxygen Reduction
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma202508055-sup-0001-SuppMat.doc30.6 MB Supporting Information References 1a) , , , Chem. Soc. Rev. 2018, 47, 7628; b) , , , , , , , , , , , Science 2019, 366, 850; c) , , , , , , , , , ACS Energy Lett. 2022, 7, 3329; d) , , , , , , , , , , Adv. Mater. 2022, 34, 2206540; e) , , , , , , , , , Appl. Catal., B 2023, 338, 123006. 2a) , , , , , , , , , , , , , J. Am. Chem. Soc.
Advances in Molecular Function and Recombinant Expression of Human Collagen
1. Introduction Collagens derived from animal tissues pose risks of allergic reactions, immunogenicity, and pathogen transmission []. In contrast, recombinant human collagens offer advantages such as high purity, non-animal sourcing, and elimination of viral or prion contamination risks [,,]. Skin defects caused by trauma or pathology often lead to infections, inflammation, chronic wounds, and scarring [,].
Finite-time bumpless transfer synchronisation of discrete-time delayed positive neural networks under dual-channel false data inject attacks
No potential conflict of interest was reported by the author(s). Data are available from the corresponding authors on reasonable request. Additional information This work is supported in part by National Natural Science Foundation of China under grants numbers 61973166.
Microscopic DIC measurement using an improved global registration image-stitching algorithm
In this study, an improved microscopic digital image correlation (DIC) measurement method using a global registration image-stitching algorithm is proposed to address the challenge of balancing strain measurement accuracy with computational efficiency in large-field microscopic measurements. First, multiple adjacent images are captured at different locations of microscopic structures.
Comparative analysis of Hyperspectral and Near-infrared Spectroscopy for Bloodstain Deposition Time Estimation
Comparative analysis of Hyperspectral and Near-infrared Spectroscopy for Bloodstain Deposition Time Estimation Background: Bloodstains are a prevalent and critical type of forensic evidence at crime scenes. Accurate determination of bloodstain age is essential for crime resolution, and non-destructive spectral methods are instrumental in this process.
Investigation of a Physical Model for the Reverse Recovery Characteristics of PT-PIN FRD with a Buffer Layer
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Self‐assembled Gap‐Rich PdMn Nanofibers with High Mass/Electron Transport Highways for Electrocatalytic Reforming of Waste Plastics
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma202411148-sup-0001-SuppMat.docx17.2 MB Supporting Information References 1a) , , , , , , , , Chem. Soc. Rev. 2023, 52, 8; b) , , , , , , , , , , Science 2023, 379, 807; c) , , , , , Nat. Commun. 2022, 13, 3343; d) , , , , , , Angew. Chem., Int. Ed. 2022, 61, 202117205. 2a) , , , , , , , , , Adv. Funct. Mater. 2024, 34, 2401796; b) , , , , , , Nat. Catal.
Developing a diversified evaluation system of student development: Innovation from education informatisation in China
Ayuda Buscar en la ayuda Buscar en la ayuda Developing a diversified evaluation system of student development: Innovation from education informatisation in China Kun Ma [1] ; Kenny Chean Soon Lee [2] ; Seng yue Wong [3] ; Xiaoli Pan [4] ; Tiantian Qi [4] ; Yunyun Wang [5] [1] PhD, Institute for Advanced Studies, Universiti Malaysia,Kuala Lumpur,Malaysia; PhD, Administrative Department, Chaoyin Education Group, China, [2] Professor,Department of Educational Management, Planning and Policy...
Mechanism and Control Strategies for Current Sharing in Multi-Chip Parallel Automotive Power Modules
Effect of an Exercise Intervention Based on General Adaptation Syndrome Model on Psychological Experience in Community-Dwelling Elderly
1. Maestas N, Mullen KJ, Powell D (2023). The effect of population aging on eco-nomic growth, the labor force, and productivity. Am Econ J-Macroecon, 15(2): 306-32. 2. van de Rijt LJ, Stoop CC, Weijenberg RA, et al (2020). The influence of oral health factors on the quality of life in older people: a systematic review. Gerontologist, 60(5): e378-94. 3. Drenth-van Maanen AC, Wilting I, Jansen PA (2020).
The Mechanism of Short-Circuit Oscillations in Automotive-Grade Multi-Chip Parallel Power Modules and an Effective Mitigation Approach
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Biomimetic Camouflaged Metal organic framework for enhanced siRNA Delivery in Tumor Environment
Biomimetic Camouflaged Metal organic framework for enhanced siRNA Delivery in Tumor Environment Gene silencing through RNA interference (RNAi), particularly using small double-stranded RNA (siRNA), has been identified as a potent strategy for targeted cancer treatment. Yet, its application faces challenges such as nuclease degradation, inefficient cellular uptake, endosomal entrapment, off-target effects, and immune responses have hindered its effective delivery.
Hepatocellular Carcinoma LINC01116 Outcompetes T Cells for Linoleic Acid and Accelerates Tumor Progression
1 Introduction Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third most common cause of cancer-related death.[1] HCC is a primary tumor caused by an increase in genomic mutational load in hepatocytes in response to multiple risk stimuli, and its occurrence may be associated with hepatitis B and C virus infection, alcohol consumption, and obesity.[2] Although there are many treatment options for HCC, due to the inconspicuous early symptoms, the rapid proliferation of...
Multiobjective Evolutionary Superpixel Segmentation for PolSAR Image Classification
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Precise Identification of Site Characteristics and Risk Management of Ningdong Coal Power Base
1. Introduction Ningdong coal power base is the most representative coal, coal power, and coal chemical industry cluster bases in China. It is one of the fourteen national large coal bases with a production capacity of 100 million tons, comprising nine large coal power bases generating 10 million kilowatts and encompassing four demonstration zones for the modern coal chemical industry [1].
Chimeric Antigen Receptor T-Cell Therapy for Glioblastoma
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Accumulation and Transport of Phthalic Acid Esters in the Soil-Plant System of Agricultural Fields with Different Years of Film Mulching
4.3. TF and BCF Characteristics of PAEs Research has shown that crops can absorb and accumulate PAEs from the soil through their root systems []. Moreover, they also can absorb and accumulate PAEs from the air through their leaf stomata []. Consuming contaminated plants is the main pathway for human exposure to harmful compounds.
Spatial and Temporal Distribution and Source Analysis of Heavy Metals in Agricultural Soils of Ningxia, Northwest of China
3.5. Quantify Sources of Soil Heavy Metals Although the positive correlations between heavy metals suggested that these elements have similar origins, the complex relationships between heavy metals were affected by various factors, so the conclusions of the correlation coefficients were not entirely comprehensive and precise [].
Temperature Gradient and Solidification Rate Simulation Model of the Microstructure of Laser-Cladded 27SiMn
3.1. The Results of Numerical Calculation A heat source was applied on the upper surface of the model. The initial conditions and boundary conditions are given in and Section 2.3, and the temperature at different times was obtained. The simulated temperature distribution profile at different time intervals of the laser beam interaction with the substrate surface is shown in Figure 5. Two semi-circle dotted curves represent the solid and liquid phase separation.
scDecouple: Decoupling cellular response from infect-ed proportion bias in scCRISPR-seq
Abstract Motivation: scCRISPR-seq is an emerging high-throughput CRISPR screening technology that combines CRISPR screening with single-cell sequencing technologies. It provides rich information on the mechanism of gene regulation. However, when scCRISPR-seq is applied in a population of heterogeneous cells, the true cellular response to perturbation is coupled with infected proportion bias of guide RNAs (gRNAs) across different cell clusters.
Failure Analysis for Gold Wire Bonding of Sensor Packaging Based on Experimental and Numerical Methods
1. Introduction The reliability of automotive sensors can be evaluated and improved by predicting their health status. Complex environmental factors, such as ambient temperature, random vibration, drop, etc., have a great impact on the reliability and lifetime of electronic components, including sensors. In this work, a sensor reliability analysis model is established according to the certification requirements of the Automotive Electronics Committee (AEC-Q100).
A Micromechanical Analysis to the Viscoplastic Behavior of Sintered Silver Joints under Shear Loading
4.3. Convergence Study The accuracy of the simulation results is influenced by the mesh size and the number of grains. To ensure the reliability of the obtained material parameters, it is essential to establish multiple simulation models. Previous research has suggested that grain orientation effectively encapsulates the impact of grain number.
Mainstreaming production and nutrient resilience of vegetable crops in megacities: pre-breeding for terrace cultivation
1 Introduction Terrace cultivation had existed since the days of Babylon in 2300 BC (Udayan and Sreedaya, 2018). While in modern societies, terraces/balconies are the only places that citizens could cultivate their own vegetables with the expanding of megacities (Chitra, 2021), so local nutrient sources are rapidly depleting, consequently hindering food supplies.
Natural products for treatment of premature ovarian failure: a narrative review
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Efficacy for Bone Deterioration in Mice with Osteoporosis and Pharmaceutical Properties of a Novel Compound Calcium Carbonate Granule
Osteoporosis (OP) has been a global health concern, and calcium supplements are still an effective method to relieve the disease. In this study, we investigated the pharmaceutical properties, antiosteoporosis, and adverse effects of a novel calcium supplement named compound calcium carbonate granule (CCCG). The dissolution rate, stability of vitamin D3, and drug permeability of the calcium supplements were explored.
Digital Finance and Advanced Manufacturing Industry Development in China: A Coupling Coordination Analysis
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Double K-Shell Ionization of Ar by 197-MeV/u Xe54+ Ion Impact
Abstract : We present an experimental study on the double K-shell ionization of argon in single collisions with the Xe54+ ion at 197 MeV/u. The X-ray spectra of multi-ionized argon are measured at the observation angles of 90° and 145° with respect to the projectile beam. The target K X-ray satellite and hypersatellite lines are analyzed with a fitting model and the cross-section ratio of double to single K-shell ionization is derived.
Study on Price Bubbles of China’s Agricultural Commodity against the Background of Big Data
Abstract : Agriculture provides a basis for social and economic development. It is therefore crucial for society and the economy to stabilize agricultural prices. Recent large increases and decreases in Chinese agricultural commodity prices have increased production risks, heightened fluctuations in the domestic agricultural supply, and impacted the stability of the global agricultural market.
A Hybrid Model Based on Improved Transformer and Graph Convolutional Network for COVID-19 Forecasting
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Yulan Li 1,2 and Kun Ma 1,* 1 Faculty of Civil Engineering and Mechanics, Kunming University of Science and Technology, Kunming 650500, China 2 Faculty of Science, Kunming University of Science and Technology, Kunming 650500, China * Author to whom correspondence should be addressed. Academic Editors: Marzieh Soltanolkottabi, Hadi Akbarzadeh Khorshidi and Sharon Lawn Int. J.
TM‐HOL: Topic memory model for detection of hate speech and offensive language
Abstract In the era of the explosion of digital content of large-scale self-media, user-friendly social platforms such as Twitter and Facebook, provide opportunities for people to express their ideas and opinions freely. Due to lack of restrictions, hateful speech and its exposure can have profound psychological impacts on society. Current social networking platform is over-reliant on the manual check, and it is labor-intensive and time-consuming.
A PLCB1-PI3K-AKT Signaling Axis Activates EMT to Promote Cholangiocarcinoma Progression
Molecular Cell Biology Shuhang Liang, Hongrui Guo, Kun Ma, Xianying Li, Dehai Wu, Yiqi Wang, Wei Wang, Shugeng Zhang, Yifeng Cui, Yufeng Liu, Linmao Sun, Bo Zhang, Mengyang Xin, Ning Zhang, Huanran Zhou, Yao Liu, Jiabei Wang and Lianxin Liu DOI: 10.1158/0008-5472.CAN-21-1538 Published December 2021 Abstract As a member of the phospholipase family, phospholipase C beta 1 (PLCB1) is involved in phospholipid hydrolysis and is frequently upregulated in human cancer.
A PLCB1-PI3K-AKT signaling axis activates EMT to promote cholangiocarcinoma progression
Research Article Shuhang Liang, Hongrui Guo, Kun Ma, Xianying Li, Dehai Wu, Yiqi Wang, Wei Wang, Shugeng Zhang, Yifeng Cui, Yufeng Liu, Linmao Sun, Bo Zhang, Mengyang Xin, Ning Zhang, Huanran Zhou, Yao Liu, Jiabei Wang and Lianxin Liu DOI: 10.1158/0008-5472.CAN-21-1538 Abstract As a member of the phospholipase family, phospholipase C beta 1 (PLCB1) is involved in phospholipid hydrolysis and is frequently upregulated in human cancer.
Cinobufagin Suppresses The Characteristics Of Osteosarcoma Cancer Cell
Cinobufagin Suppresses The Characteristics Of Osteosarcoma Cancer Cells By Inhibiting The IL-6-OPN-STAT3 Pathway Video abstract presented by Chuan Zhang.
Cancer cell targeting, controlled drug release and intracellular fate of biomimetic membrane-encapsulated drug-loaded nano-graphene oxide nanohybrids
Nano-graphene oxide (NGO) has been proposed as a novel drug carrier. However, its poor biocompatibility and physiological stability as well as the lack of cancer targeting ability have limited its further application in cancer therapy.
Intestinal dysbiosis activates renal renin-angiotensin system contributing to incipient diabetic nephropathy
1. Institute of Nephrology, Zhong Da Hospital, School of Medicine, Southeast University, Nanjing City, Jiangsu Province, China. 2. Centre for Nephrology, University College London (UCL) Medical School, Royal Free Campus, UK. This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
NMR studies of the interactions between AMB-1 Mms6 protein and magnetosome Fe3O4 nanoparticles
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