Kunwu Yu on Muck Rack

Kunwu Yu

As seen in: Color Research & Application
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Articles

CD4+CD25+ GARP+ Tregs display a compromised suppressive function in patients with dilated cardiomyopathy

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By Yuzhen Wei, Xin Su, Haitao Sun, Quan Luo, Wenbin Xu, Kunwu Yu, Hui Wei, Ruirui Zhu, Huairui Shi, Junhui Xiao, Yucheng Zhong, Qiutang Zeng
| Color Research & Application Verified
Dilated cardiomyopathy (DCM) is a lethal inflammatory heart disease and closely connected with dysfunction of the immune system. Glycoprotein -A repetitions predominant (GARP) expressed on activated CD4+ T cells with suppressive activity has been established. This study aimed to investigate the frequency and function of circulating CD4+CD25+GARP+ regulatory T cells (Tregs) in DCM. 45 DCM patients and 46 controls were enrolled in this study.
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