Skip to main content
Kuo Hao Lee on Muck Rack

Kuo Hao Lee

As seen in: ACS Publications, BioRxiv
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Kuo Hao

Contact Kuo Hao, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Decoding the Structure–Activity Relationship of the Dopamine D3 Receptor-Selective Ligands Using Machine and Deep Learning Approaches

|
By Sung Won, Kuo Hao Lee, Rey Y. Capangpangan
| ACS Publications
Open in Who Shared Issue with article?

Decoding the Structure–Activity Relationship of the Dopamine D3 Receptor-Selective Ligands Using Machine and Deep Learning Approaches

|
By Sung Won, Kuo Hao Lee, Rey Y. Capangpangan
| dx.doi.org
Open in Who Shared Issue with article?

Linkers in bitopic agonists shape bias profile among transducers for the dopamine D2 and D3 receptors

|
By Ana Semeano, Alessandro Bonifazi, Kuo Hao Lee, Rian Garland
| BioRxiv
Abstract Bitopic ligands bind both orthosteric and allosteric or secondary binding sites within the same receptor, often resulting in improvement of receptor selectivity, potency, and efficacy. In particular, for both agonists and antagonists of the dopamine D2 and D3 receptors (D2R and D3R), the primary therapeutic targets for several neurological and neuropsychiatric disorders, bitopic ligand design has proved advantageous in achieving better pharmacological profiles in vitro.
Open in Who Shared Issue with article?
See all 7 articles