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KV Nageswar on Muck Rack

KV Nageswar

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Articles

Non-canonical pore architecture underlies constitutive gating of human retinal TRPM1

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By Mansi Sharma, Vikesh Kumar, Rohit Chettri, Sristi Nanda, Kirill A. Martemyanov, Appu Kumar Singh, KV Nageswar, Ankur Chattopadhyay, Nishtha Varshney
| Nature Verified
Abstract Transient receptor potential melastatin 1 (TRPM1), a Ca²⁺-permeable nonselective cation channel essential for retinal ON bipolar cell signaling and night vision, and implicated in congenital night blindness, has remained structurally and functionally poorly characterized.
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