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Kyra L. Jordan on Muck Rack

Kyra L. Jordan

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The effect of weight-loss surgery in patients with obesity on adipose tissue mesenchymal stem cells versus circulating endothelial progenitor cells

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By Ning Yang, Mina Al Saeedi, Xiangyang Zhu, Hui Tang, Aleksandra Kukla, Alfonso Eirin, Amir Lerman, Lilach O. Lerman, Ailing Xue, Negin Mahmoudi Hamidabad, Kyra L. Jordan
| Nature Verified
Abstract Obesity imposes dysfunction of the endogenous cellular reparative system, which may manifest as impaired adipose tissue-derived mesenchymal stem/stromal cells (AT-MSCs) function or altered characteristics of circulating endothelial progenitor cells (EPCs). However, whether both systems are abnormal in patients with obesity remains unclear. We hypothesized that human obesity induces impairment of MSCs and EPCs that would be reversed after weight-loss surgery (WLS).
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