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Kyun-Seop Bae on Muck Rack

Kyun-Seop Bae

Seoul
As seen in: Wiley Online Library, International Journal of Nursing Studies, MDPI
Professor of Clinical Pharmacology; New Drug Development Scientist; Pharmacometrician
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Articles

First‐In‐Human Dose Finding Study of Venadaparib (IDX‐1197), a Potent and Selective PARP Inhibitor, in Patients With Advanced Solid Tumors

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By Sung-Bae Kim, Kyun-Seop Bae, Won Sik Lee, Jae Lee
| Wiley Online Library Verified
1 Introduction The poly (ADP-ribose) polymerase (PARP) is a ubiquitous nuclear enzyme involved in DNA repair. It catalyzes the transfer of ADP-ribose to target proteins (PARylation) by utilizing nicotinamide adenine dinucleotide (NAD+) [1]. Among the 17 PARP family members, PARP-1 and PARP-2 are involved in DNA damage repair and are essential for cell survival [2]. Many proteins are involved in the DNA damage response (DDR), which can be affected by alterations in those proteins.
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A Comparison of the Charlson and Elixhauser Methods for Predicting Nursing Indicators in Gastrectomy with Gastric Cancer Patients

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By Chul-Gyu Kim, Kyun-Seop Bae
| MDPI
Abstract : Background: Comorbidity indices such as Charlson’s (CCI) and Elixhauser’s (ECI) are used to adjust the patient’s care, depending on the severity of their condition. However, no study has compared these indices’ ability to predict nursing-sensitive outcomes (NSOs). We compared the performance of CCI and ECI in predicting NSOs in gastric cancer patients’ gastrectomy.
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Relationship between nurse staffing level and adult nursing-sensitive outcomes in tertiary hospitals of Korea: Retrospective observational study

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By Chul-Gyu Kim, Kyun-Seop Bae
| International Journal of Nursing Studies Verified
Publication HistoryPublished online: January 02, 2018Accepted: January 1, 2018; Received in revised form: December 28, 2017; Received: March 1, 2017;
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