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L. Marcélis on Muck Rack

L. Marcélis

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Towards mismatched DNA photoprobes and photoreagents: “elbow-shaped” Ru(II) complexes

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By Universite Grenoble-Alpes, Q. Deraedt, L. Marcélis, F. Loiseau
| Chemistry World Verified
Due to their potentially harmful consequences, the detection of mismatched DNA is a subject of high interest. In order to probe DNA mismatches by means of luminescent sensitive Ru( ) complexes, “elbow-shaped” extended planar ligands based on an acridine or phenazine core have been synthesized (npp = naphtho[1,2-b]pyrido[3,2-f][1,7]phenanthroline and bdppz = benzo[h]dipyrido[3,2-a:2?,3?-c]phenazine).
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