Laboratoire GBCM

1 Introduction Peptides combine a variety of properties and biological activities that have aroused a growing interest in the biomedical field. They are involved in many human biological processes, such as the regulation of blood sugar levels through insulin [1], the functioning of the nervous system through neuropeptides [2], or the immune response through antimicrobial peptides that protect the body against infection [3].

The critical involvement of protein–protein interactions in essential biological processes, including immunity and inflammation, has been well-established (Braun and Gingras 2012). To explore the geometry of these interactions, researchers have utilized protein–protein docking simulations, which aim to predict the relative position of the involved proteins.