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Laboratorio Metalli

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Articles

Thioredoxin Reductase as a Target for Antibacterial Gold Compounds in Burkholderia cenocepacia : Disclosing the Molecular Basis of Enzyme Inhibition

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By Stefano Zineddu, Laboratorio Metalli, José Aleixo de Azevedo-França
| Wiley Online Library Verified
1 Introduction Antibiotic resistance is one of the most pressing challenges in modern medicine. The rapid emergence and global spread of multidrug-resistant bacteria threaten decades of therapeutic progress and are projected to cause up to 10 million deaths a year by 2050 [1]. Inappropriate antibiotic use in healthcare and agriculture has significantly accelerated this phenomenon.
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