Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Lang Pan
8-Oxoguanine DNA Glycosylase1 conceals oxidized guanine in nucleoprotein-associated RNA of respiratory syncytial virus
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Pan L, Wang K, Hao W, Xue Y, Zheng X, Basu RS, et al. (2024) 8-Oxoguanine DNA Glycosylase1 conceals oxidized guanine in nucleoprotein-associated RNA of respiratory syncytial virus. PLoS Pathog 20(10): e1012616.
OGG1 as an Epigenetic Reader Affects NFκB: What This Means for Cancer
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Device-measured movement behaviours in over 20,000 China Kadoorie Biobank participants - International Journal of Behavioral Nutrition and Physical Activity
A general description of the CKB study concerning the study population, baseline data collection, and follow-up procedures has been reported elsewhere [20, 21]. Briefly, trained investigators conducted a baseline survey between 2004–2008.
OGG1-DNA interactions facilitate NF-κB binding to DNA targets
Our previous work has established that OGG1 can augment a subset of cytokine and chemokine gene expression in mouse lung28,30,31, including CXCLs, CCLs, ILs and TNF?. To confirm that OGG1 facilitates gene expression through promoter activation, we carried out small interfering RNA (siRNA)-mediated Ogg1 knockdown and monitored how it affects luciferase activity. We were able to attain ~70% siOgg1 knockdown compared with control non-specific siRNA (Fig. 1a, insert).
Oxidized Guanine Base Lesions Function in 8-Oxoguanine DNA Glycosylase-1-mediated Epigenetic Regulation of Nuclear Factor κB-driven Gene Expression
A large percentage of redox-responsive gene promoters contain evolutionarily conserved guanine-rich clusters; guanines are the bases most susceptible to oxidative modification(s). Consequently, 7,8-dihydro-8-oxoguanine (8-oxoG) is one of the most abundant base lesions in promoters and is primarily repaired via the 8-oxoguanine DNA glycosylase-1 (OOG1)-initiated base excision repair pathway.
Oxidized Guanine Base Lesions Function in 8-Oxoguanine DNA Glycosylase1-Mediated Epigenetic Regulation of Nuclear Factor kappaB-Driven Gene Expression
A large percentage of redox-responsive gene promoters contain evolutionarily conserved guanine-rich clusters; guanines are the bases most susceptible to oxidative modification(s). Consequently, 7,8-dihydro-8-oxoguanine (8-oxoG) is one of the most abundant base lesions in promoters and is primarily repaired via the 8-oxoguanine DNA glycosylase1 (OOG1)-initiated base excision repair pathway.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Lang
Contact Lang, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack