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Lap Thi Nguyen on Muck Rack

Lap Thi Nguyen

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Articles

Multi-objective reinforcement learning for optimizing JAK/STAT pathway interventions: a quantitative systems pharmacology study for preclinical drug development

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By Nhung Duong, Tien Nguyen Verified, Khánh Phan, Tuan Ngoc Do, Hoa Dinh Vu, Lap Thi Nguyen
| Nature Verified
Abstract Treatment optimization targeting JAK/STAT inhibition remains challenging due to pathway complexity and competing clinical objectives. We developed a computational framework integrating mechanistic modeling with multi-objective reinforcement learning to identify potential intervention strategies for preclinical development.
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