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Articles by Lars Bertram
Comprehensive cross-sectional and longitudinal comparison of sixteen markers of biological aging from the Berlin Aging Study II
Abstract The disproportionate increase in lifespan compared to healthspan over the past decades results in a growing proportion of life marked by diseases, even if incidence rates are falling in some cases. However, not everyone ages at the same pace and some people remain in good health and preserve physical and cognitive function into old age. To quantify inter-individual differences in the biological aging process, numerous indicators of biological age have been developed.
DNA methylation age acceleration is associated with risk of diabetes complications - Communications Medicine
Abstract Background Patients with Type 2 diabetes mellitus (T2D) are at risk for micro- and macrovascular complications. Implementable risk scores are needed to improve targeted prevention for patients that are particularly susceptible to complications. The epigenetic clock estimates an individual’s biological age using DNA methylation profiles.
Genome-wide analysis furthers decoding of Alzheimer disease genetics - Nature Reviews Neurology
A new genome-wide association study has identified 41 previously unknown loci associated with Alzheimer disease. However, these data provide limited insight into disease mechanisms or benefits for clinical prediction of Alzheimer disease. Refers to Bellenguez, C. et al. New insights into the genetic aetiology of Alzheimer’s disease and related dementias. Nat. Genet. https://doi.org/10.1038/s41588-022-01024-z (2022).
Jordens undergang er en dårlig investering
Havstigninger, skovrydning og dyreudryddelse er blevet en alvorlig risiko ved investeringer, der ikke er bæredygtige, men vi skal passe på, at der ikke går CO2 i det hele. 19.11.2021 kl. 07:30 Som professionel investor beregner vi mange forskellige risici, før vi placerer pengene, og i de senere år er ”bæredygtighedsrisikoen” begyndt at fylde meget i det regnestykke. Pessimisterne ville sige ”undergangsrisikoen”, men vi taler om det samme.
Alzheimer disease risk genes: 29 and counting
The risk of Alzheimer disease is substantially influenced by genetic factors. A new genome-wide association study of more than 600,000 individuals identifies nine novel Alzheimer disease risk genes, raising the total count of independent risk loci to 29. Access optionsAccess options Subscribe to Journal Get full journal access for 1 year $213.00 only $17.75 per issue All prices are NET prices. VAT will be added later in the checkout.
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