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Lars Ole Schwen on Muck Rack

Lars Ole Schwen

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Articles

Joint zonated quantification of multiple parameters in hepatic lobules

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By Hendrik Laue, Mohamed Albadry, Christiane Engel, Nick Weiss, Uta Dahmen, Lars Ole Schwen, Daniel Budelmann
| Nature Verified
Abstract Many liver diseases have a distinct zonation pattern. Similarly, most metabolic processes in the hepatic lobule are also spatially organized. Understanding the interplay between a zonated disease pattern and its impact on zonated metabolic liver function requires the joint quantification of both phenomena.
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Quantification of Hepatic Vascular and Parenchymal Regeneration in Mice

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By Chichi Xie, Lars Ole Schwen, Weiwei Wei, Andrea Schenk
| PLOS
Liver regeneration consists of cellular proliferation leading to parenchymal and vascular growth. This study complements previous studies on cellular proliferation and weight recovery by (1) quantitatively describing parenchymal and vascular regeneration, and (2) determining their relationship. Both together are needed to (3) characterize the underlying growth pattern.
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