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Laura Mandefield

As seen in: BMJ Open, BMJ Paediatrics & Child Health, The Lancet
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Articles by Laura Mandefield

The diabetic foot after SWHSI-2: healing is not one size fits all - Authors' reply

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By Catherine Arundel, Laura Mandefield, Caroline Fairhurst, Ian Chetter
| The Lancet Verified
CorrespondenceVolume 406, Issue 10522p2925-2926 aYork Trials Unit, University of York, York YO10 5DD, UK bFaculty of Health Sciences, University of Hull, Hull, UK cHull York Medical School, Hull, UK dHull University Teaching Hospitals NHS Trust, Hull, UK Publication History: Published December 20, 2025 DOI: 10.1016/S0140-6736(25)02247-0 External LinkAlso available on ScienceDirect External Link Copyright: © 2025 Elsevier Ltd.
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Negative pressure wound therapy versus usual care in patients with surgical wound healing by secondary intention in the UK (SWHSI-2): an open-label, multicentre, parallel-group, randomised controlled trial

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By Catherine Arundel, Laura Mandefield, Caroline Fairhurst, Pedro Saramago
| The Lancet Verified
Introduction Healing by secondary intention refers to a strategy to heal wounds by leaving skin edges unopposed. This method requires the growth of granulation tissue from the base of the wound and might be preferred in areas where there is contamination, or inability to achieve primary skin cover.
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Preliminary results on validity and reliability from two prospective cohort studies on a new Neonatal Coma Score

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By Anthony Hart, Elizabeth Matthews, Laura Mandefield, Martha Kieran
| BMJ Paediatrics & Child Health
Abstract Objective To collect data on content/face validity and interobserver agreement for a Neonatal Coma Score (NCS) in well full-term neonates and on construct validity in unwell and preterm babies, specifically how the NCS changed with gestational age and illness. Design Prospective cohort studies. Setting Two UK tertiary neonatal units (Sheffield and Leeds).
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Feasibility study for supporting medication adherence for adults with cystic fibrosis: mixed-methods process evaluation

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By Daniel Thomas Hind, Sarah Drabble, Madelynne Arden, Laura Mandefield
| BMJ Open Verified
Feasibility study for supporting medication adherence for adults with cystic fibrosis: mixed-methods process evaluation http://orcid.org/0000-0002-6409-4793Daniel Hind1, Sarah J Drabble2, Madelynne A Arden3, Laura Mandefield4, Simon Waterhouse1, Chin Maguire1, Hannah Cantrill1, Louisa Robinson1, Daniel Beever1, http://orcid.org/0000-0001-7426-7099Alex Scott1, Sam Keating1, Marlene Hutchings5, Judy Bradley6, Julia Nightingale7, Mark I Allenby7, Jane Dewar8, Pauline Whelan9, John Ainsworth9,...
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