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Laura Pyle on Muck Rack

Laura Pyle

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Articles

Interpersonal psychotherapy for adolescent gestational weight gain and wellbeing: pilot and feasibility randomised controlled trial

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By Lauren D Gulley, Laura Pyle, Steffany Joslin
| Taylor & Francis Online
ABSTRACT Aims/Background Pregnant adolescents face adversities that heighten perinatal complications in mental (e.g. depression) and physical (e.g. excess gestational weight gain [GWG]) health. Depression may affect excess GWG through stress-related behaviours. We sought to pilot feasibility/acceptability of integrating a brief mental health intervention within prenatal care to address depression and stress-related behaviours contributing to excess GWG.
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Hypoxia inducible factor network reflects kidney disease progression in diabetes and sodium-glucose co-transporters inhibition

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By Viji Nair, Akihiro Minakawa, Cathy Smith, Celine C. Berthier, John J. Hartman, Rajasree Menon, Damian Fermin, Edgar A. Otto, Debora L Gisch, Michael T. Eadon, Sanjay Jain, Ye Ji Choi, Laura Pyle, Fadhl M Alakwaa, Michael Rose, Lalita Subramanian, Jamal Saghir, Jeffrey A. Beamish, Jeffrey B. Hodgin, Frank C. Brosius, Petter Bjornstad, Peter Nelson, Jennifer Harder, Thomas Werner, Matthias Kretzler, Jennifer Schaub, Felix Eichinger
| Nature Verified
Abstract Hypoxia drives diabetic kidney disease (DKD) progression through Hypoxia Inducible Factor (HIF) signaling. The kidney’s cellular heterogeneity and complex architecture pose challenges for directly assessing the pharmacologic effects on kidney oxygenation and hypoxia-responsive pathways in vivo, such as treatment with SGLT2 inhibitors (SGLT2i), presumed to impact kidney oxygenation.
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Impact of Vertical Sleeve Gastrectomy in Youth‐Onset Type 2 Diabetes: Changes in Glycemia, Insulin Sensitivity, and Secretion

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By Tyler Dobbs, Laura Pyle, Jaime Moore
| Wiley Online Library Verified
Conflicts of Interest P.B. reports serving or having served as a consultant for AstraZeneca, Bayer, Bristol-Myers Squibb, Boehringer Ingelheim, Eli-Lilly, LG Chemistry, Sanofi, Novo Nordisk, and Horizon Pharma. P.B. also serves or has served on the advisory boards and/or steering committees of AstraZeneca, Bayer, Boehringer Ingelheim, Novo Nordisk, and XORTX. M.G.C. serves as site PI for Eli-Lilly and Amino CO and consultant for Eli-Lilly and Novo Nordisk.
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