Research suggests that some older adults with stable multiple sclerosis may not need a disease-modifying therapy. Bezzy MS readers share their insights into how stopping their DMTs has affected them. Disease-modifying therapies (DMTs) have drastically improved the lives of millions of people with multiple sclerosis (MS) since they were introduced in the 1990s. Now, with nearly 30 approved DMTs available, people with MS can treat their disease with a pill, an injection, or an infusion.