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Lawrence Barnes

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Articles

Safety and immunogenicity of concomitant quadrivalent meningococcus ACYW-TT and meningococcus group B vaccines

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By Monica McArthur, Adam Finn, Lawrence Barnes, Katrina Cathie, Eva P. Galiza, Paul Heaton, Nicholas Jacobsen, Stephen Jones, Siân Ludman, Patrick Moore, Clare Murray, Daniel Owens, Ray Borrow, Julie Chaix, Youjun Huang, Olga Syrkina, Betzana Zambrano, Mandeep Singh Dhingra, Christine Rehm, Richard Burkimsher, Alexander Trotman, Arlette Delgado, Estelle Dubois
| Nature Verified
Abstract Infants are vulnerable to meningococcal disease. In this open-label phase III study (NCT03632720; registered 13/8/2018), infants were randomised to quadrivalent ACWY conjugated vaccine, MenACYW-TT, at 3 and 12–13 months and four-component meningococcus group B vaccine (4CMenB) at 2, 4, and 12–13 months (Group 1), MenACYW-TT at 3 and 12–13 months and 4CMenB at 2 and 4 months (Group 2), or 4CMenB at 2, 4, and 12–13 months (Group 3). Routine vaccines were also administered per UK schedule.
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