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Articles by Lawrence MS
Expression characterization of the guanylate-binding protein gene family in breast cancer and its association with the immune microenvironment
Expression characterization of the guanylate-binding protein gene family in breast cancer and its association with the immune microenvironment 1Department of Science and Education, Nanshan Maternity and Child Healthcare Hospital, Shenzhen, China 2Administration Office, Nanshan Maternity and Child Healthcare Hospital, Shenzhen, China 3Laboratory Medicine, Nanshan Maternity and Child Healthcare Hospital, Shenzhen, China DOI 10.7717/peerj.20058 Academic Editor Fanglin Guan Subject Areas...
NCBP2 predicts the prognosis and the immunotherapy response of cancers: a pan-cancer analysis
Transcriptional data and clinical information from the TCGA Pan-cancer cohort, as well as normal human tissue data from the Genotype-tissue expression (GTEx) database, were acquired through university of Cingifornia Sisha Cruz (UCSC) Xena (Goldman et al., 2020) (https://xenabrowser.net/). The expression of NCBP2 in TCGA and GTEx datasets was analyzed with transcripts per million (TPM) using the same sequencing platform and library preparation to reduce potential batch effects.
Alteration of RNA m6A methylation mediates aberrant RNA binding protein expression and alternative splicing in condyloma acuminatum
Approval for this study was obtained from the Institutional Review Board of the First Affiliated Hospital, School of Medicine of Zhejiang University (2022-795). Written informed consent was obtained from all subjects. The flow of the procedural steps in our study is shown in Fig. 1. CA female patients aged 20-40 years old with positive HPV genotyping were included, and those complicated with tumors, other immunocompromised diseases and other sexually transmitted diseases were excluded.
Integrating multi-type aberrations from DNA and RNA through dynamic mapping gene space for subtype-specific breast cancer driver discovery
Discussion Discovering subtype-specific drivers is an inevitable demand in breast cancer precision medicine. The existing widely-used computational tools for driver discovery mainly focus on exploiting the information from DNA aberrations or gene interactions.
13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking
Lymphoid Neoplasia| August 20, 2020 You do not currently have access to this content.
LUBAC accelerates B-cell lymphomagenesis by conferring resistance to genotoxic stress on B cells
Lymphoid Neoplasia| August 6, 2020 You do not currently have access to this content.
Rare and private spliceosomal gene mutations drive partial, complete, and dual phenocopies of hotspot alterations
MYELOID NEOPLASIA| March 26, 2020
Stem cell donors should not be screened for clonal hematopoiesis
COUNTERPOINT| February 25, 2020
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