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Articles by Lee SO
Anticancer Effects of Broccoli Sprout Extract and Sulforaphane Through ROS-Induced MAPK Pathway in Breast Cancer Cells and Xenografts.
Abstract <p>Breast cancer treatment remains challenging due to therapeutic resistance and the limited availability of effective molecular targets. We investigated the anticancer effects of sulforaphane (SFN) and broccoli sprout extract (BSE), an SFN-enriched phytochemical formulation, in MCF7 and MDA-MB-231 breast cancer cells.
Computed tomography-derived body composition parameters as potential predictors of severity and adverse outcomes in viral pneumonia: a retrospective study
This study investigated the value of chest CT-derived body composition parameters and clinical risk factors in predicting viral pneumonia severity. Patients were categorized into severe and non-severe groups, and a subgroup analysis of 30-day adverse outcomes was performed in the severe group. Although both the clinical and imaging models demonstrated good predictive performance, the combined model showed improved accuracy, as evidenced by an increase in the AUC from 0.796 and 0.735 to 0.843.
Immune-neural regulatory mechanism of osteoporosis induced by androgen deficiency
Osteoporosis, caused by an imbalance in bone conversion between resorption and formation, is a key health problem worldwide. Hormone deficiencies are closely linked to primary osteoporosis, disrupting the delicate balance of bone remodeling. The decline in hormone levels following menopause in women, as well as the reduction of estrogen and androgens in older men can lead to the development of osteoporosis (Almeida et al., 2017).
UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair
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Risk and Outcome of Infective Endocarditis in Streptococcal Bloodstream Infections according to Streptococcal Species
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3-Deoxysappanchalcone Inhibits Cell Growth of Gefitinib-Resistant Lung Cancer Cells by Simultaneous Targeting of EGFR and MET Kinases
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Flavone and Hydroxyflavones Are Ligands That Bind the Orphan Nuclear Receptor 4A1 (NR4A1)
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Adequacy of the examination-based licensing system and a training-based licensing system for midwifery license according to changes in childbirth medical infrastructure in Korea: a survey-based descriptive study - PubMed
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