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Leon Hubbard

As seen in: JAMA Psychiatry
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Articles

Association of Genetic Risk for Schizophrenia With Nonparticipation Over Time in a Population-Based Cohort Study

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By Kate Tilling, Leon Hubbard, Evie Stergiakouli, George Smith, Anita Thapar, Michael C. O'Donovan
| The World Bank Research Observer Verified
Progress has recently been made in understanding the genetic basis of schizophrenia and other psychiatric disorders. Longitudinal studies are complicated by participant dropout, which could be related to the presence of psychiatric problems and associated genetic risk.
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Phenotypic Manifestation of Genetic Risk for Schizophrenia During Adolescence in the General Population

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By Hannah J. Jones, Evie Stergiakouli, Katherine E. Tansey, Leon Hubbard, Jon Heron
| JAMA Psychiatry Verified
Importance  Schizophrenia is a highly heritable, polygenic condition characterized by a relatively diverse phenotype and frequent comorbid conditions, such as anxiety and depression. At present, limited evidence explains how genetic risk for schizophrenia is manifest in the general population. Objective  To investigate the extent to which genetic risk for schizophrenia is associated with different phenotypes during adolescence in a population-based birth cohort.
Open in Who Shared Issue with article?
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