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Leonardo Bufi on Muck Rack

Leonardo Bufi

As seen in: Dove Medical Press
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Articles

Prevalence of Elevated Lipoprotein(a) and Its Association with Cardiovascular Disease in Patients with Overweight and Obesity in Argentina

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By Ezequiel Forte, Matias Fernando Arrupe, Leonardo Bufi
| Dove Medical Press
Introduction Lipoprotein(a) (Lp(a)) is a cholesterol-rich lipoprotein particle composed of an apolipoprotein B-100 molecule covalently bound to apolipoprotein(a). Elevated Lp(a) is independently associated with a higher risk of atherosclerotic cardiovascular disease (ASCVD), including ischemic heart disease (IHD), stroke, and calcific aortic valve stenosis.1 Lp(a) levels are largely genetically determined and exhibit minimal intraindividual variability.
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