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Abstract PHERGain was a randomized, non-comparative phase 2 trial evaluating a positron 18F-fluorodeoxyglucose-positron emission tomography (18F-FDG-PET)-guided, pathological complete response (pCR)-adapted strategy to omit chemotherapy in HER2-positive early breast cancer. Female patients with HER2-positive stages I–IIIA operable breast cancer (tumor size ≥ 1.5 cm) were randomized to receive chemotherapy plus trastuzumab and pertuzumab (HP; group A) or HP ± endocrine therapy (group B).
Abstract Manual data entry and curation is the most used method of data collection for real world evidence and clinical trials but is a time-consuming task associated with significant human effort and transcription mistakes. MIRROR is a retrospective study that compared manual data capture from electronic case report forms (eCRF) to automated data extraction from electronic health records (EHRs) using artificial intelligence (AI).
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