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Peritumoural adipose tissue drives immune evasion in colorectal cancer via adipose–mesenchymal transformation - Nature Cell Biology
Abstract Although peritumoural visceral adipose tissue (tVAT) is anatomically close to tumours such as colorectal cancer, the immune landscape of this tissue and its functional contribution to tumour immunity remain poorly defined. Here, we performed single-cell RNA analysis on the tVAT from patients with colorectal cancer to map its immune landscape and observed that tVAT exhibited a highly immune-infiltrated microenvironment enriched with lymphocytes, especially tumour-specific CD8⁺ T cells.
Targeting Lactate: An Emerging Strategy for Macrophage Regulation in Chronic Inflammation and Cancer
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Hierarchical Branched TiO2 Photo/Photoelectrocatalyst with Directed Charge Transfer for Efficient Hydrogen Production from Seawater
Energy, Environmental, and Catalysis ApplicationsAugust 30, 2024 Yi-Xuan Liu State Key Laboratory of Advanced Technology for Materials Synthesis and Processing & School of Materials Science and Engineering & Shenzhen Research Institute & Laoshan Laboratory, Wuhan University of Technology, Wuhan, Hubei 430070, People’s Republic of China * Yi Lu State Key Laboratory of Advanced Technology for Materials Synthesis and Processing & School of Materials Science and Engineering & Shenzhen Research...
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