Liang-Kai Chu on Muck Rack

Liang-Kai Chu

As seen in: AIChE Journal, MDPI
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Articles

Use of LC‐MS to characterize host cell protein removal during depth filtration

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By Liang-Kai Chu, Ehsan Espah Borujeni, Bristol Myers Squibb, Biologics Development
| AIChE Journal Verified
1 INTRODUCTION The removal of host cell proteins (HCP) is a critical component of the downstream process in the production of biopharmaceuticals.
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Enhancing the Performance of Tangential Flow Microfiltration for Bioreactor Clarification

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By Liang-Kai Chu, Xianghong Qian, John Paul Smelko, Amir Hossein Mostafavi
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Detergent/surfactant retention during ultrafiltration in the formulation of biotherapeutics

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By Zhuoshi Du, Matthew Billups, Hee Jeung Oh, Liang-Kai Chu
| AIChE Journal Verified
1 INTRODUCTION Surfactants like polysorbates (also known by the commercial name Tween®) are extensively used as stabilizers in the formulation of therapeutic proteins.
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